Scientists create bee vaccine to fight off ‘insect apocalypse’

A vaccine developed by a team at Helsinki University gives bees resistance to fight off severe microbial diseases that can be fatal for pollinator communities. | AFP-JIJI

Scientists in Finland have developed the first vaccine to protect bees against disease, raising hopes for tackling the drastic decline in insect numbers, which could cause a global food crisis.

Bees are vital for growing food, as they help fertilize 3 out of 4 crops by transferring pollen from male to female flowers.

But in recent years bee populations have been dying off from colony collapse disorder, a mysterious scourge blamed on mites, pesticides, virus, fungus or some combination of these factors.

U.N.-led research in 2016 found that more than 40 percent of invertebrate pollinators, particularly bees and butterflies, are facing extinction.

The study also found that 16.5 percent of vertebrate pollinators, such as birds and bats, are under threat.

Scientists warn that the die-off will result in higher food prices and the risk of shortages.

The vaccine, developed by a team at Helsinki University, gives bees resistance to fight off severe microbial diseases that can be fatal for pollinator communities.

“If we can save even a small part of the bee population with this invention, I think we have … saved the world a little bit,” lead researcher Dalial Freitak said. “Even a 2 to 3 percent increase in the bee population would be humongous.”

Vaccinating insects was previously thought to be impossible because they lack antibodies, one of the key mechanisms humans and other animals use to fight disease.

But a breakthrough came in 2014 when Freitak, a specialist in insects and immunology, noticed that moths fed certain bacteria can pass on immunity to their offspring.

“They could actually convey something by eating. I just didn’t know what the mechanism was,” Freitak said.

“I met with Heli Salmela, who was working on honeybees and a protein called vitellogenin. I heard her talk and I was like, ‘OK, I could make a bet that it is your protein that takes my signal from one generation to another.'”

The pair started to collaborate and created a vaccine against American foulbrood, the most globally widespread and destructive bee bacterial disease.

The treatment is administered to the queen bee via a sugar lump, similar to polio vaccines. The queen then passes the immunity to her offspring.

The team has begun trying to raise funding to make the vaccine commercially available, with “very positive” feedback so far, according to Freitak.

“There are many regulatory hurdles. Four to five years until reaching the market is an optimistic estimate,” she said.

Diseases are believed to be just one of a number of reasons for the loss of pollinators, alongside pesticides and intensive farming, which reduces the diversity of insects’ nutrition.

But the team believes that protecting bee populations against disease will make them stronger, and therefore better able to withstand the other threats.

The European Union and Canada have voted to introduce bans on insecticides based on neonicotinoids after studies showed the chemicals harmed the ability of bees to reproduce.

U.N.-backed research in 2016 estimated that up to $577 billion worth of food grown every year relies directly on pollinators.

The study said the volume of food produced that depends on pollinators has risen by 300 percent in the last half a century.

As pollinator numbers have declined, some farmers have turned to either renting bees or pollinating by hand — as with fruit trees in some parts of China — in order to replace the processes that nature previously provided free of charge.

In Helsinki the project relied on external funding, but the team has now taken up a more secure tenure at Graz University in Austria, where further research on vaccinations will begin early next year.

Graz is also the previous seat of noted zoologist Karl von Frisch, whose discovery that honey bees communicate by performing the figure-of-eight “waggle dance” won him the Nobel Prize in medicine in 1973.

Source; The Japan Times